The medical image community embraced open source as a standard practice back in 2000, with the adoption of the Insight Toolkit (ITK). ITK is sponsored by the US National Library of Medicine and was built as a C++ library. It is the equivalent to a usable encyclopedia of image processing algorithms.
The scientific journal, Nature Methods, has made a transformation. From closed to open, the journal now embraces open science practices with the purpose of enabling true reproducible research. This is an account of how this transformation came to be.