Dan, I'm sorry to hear about your mouse trouble. If you want to give it another go, can I suggest asking a local Linux Users Group (LUG) for help. The strange thing about Open Source is that people will go out of their way to help each other.
By the way, there are plenty of FDA approved Medical Devices that run Linux. Medical Device standards like ISO 13485 and IEC 60601-1 are all about change control, QA, and risk management.